| 1 | |  Saint Louis City SC 2 | 28 | 17 | 6 | 5 | 60 | 37 | 23 | 62 | G02:00 | 25/08/25 | R 1  Saint Louis City SC 2 3 Sporting Kansas City II 0 M03:00 | 01/09/25 | R 1 Houston Dynamo 2 (4) 2 Saint Louis City SC 2 (3) 2 G03:00 | 13/09/25 | R 1 Saint Louis City SC 2 (3) 1 Minnesota United FC 2 (2) 1 G03:30 | 20/09/25 | R 1 Austin FC II 1 Saint Louis City SC 2 2 G00:00 | 29/09/25 | R 1 Saint Louis City SC 2 (4) 1 Los Angeles FC 2 (2) 1 M23:00 | 05/10/25 | R 1 Portland Timbers II 2 Saint Louis City SC 2 1 |
| 2 | |  New York Red Bulls II | 28 | 17 | 5 | 6 | 68 | 56 | 12 | 58 | G02:00 | 25/08/25 | R 1 New York Red Bulls II 1 Chicago Fire FC II 0 G02:00 | 01/09/25 | R 1 New York Red Bulls II 7 Columbus Crew 2 4 G03:00 | 14/09/25 | R 1 Huntsville City FC 2 New York Red Bulls II 3 M00:00 | 22/09/25 | R 1 New York Red Bulls II (2) 1 Inter Miami CF II (4) 1 M02:30 | 02/10/25 | R 1 FC Cincinnati 2 2 New York Red Bulls II 1 G20:00 | 05/10/25 | R 1 New York Red Bulls II 2 Toronto FC II 1 |
| 3 | |  Philadelphia Union II | 28 | 15 | 8 | 5 | 64 | 34 | 30 | 58 | M22:00 | 24/08/25 | R 1 Philadelphia Union II 1 New England Revolution II 3 G02:30 | 01/09/25 | R 1 FC Cincinnati 2 1 Philadelphia Union II 2 G22:00 | 14/09/25 | R 1 Columbus Crew 2 1 Philadelphia Union II 3 G22:00 | 21/09/25 | R 1 Philadelphia Union II 5 Chicago Fire FC II 2 G02:00 | 27/09/25 | R 1 Toronto FC II 1 Philadelphia Union II 2 G20:00 | 05/10/25 | R 1 Philadelphia Union II 4 New York City FC II 3 |
| 4 | |  New England Revolution II | 28 | 14 | 7 | 7 | 54 | 37 | 17 | 54 | G02:00 | 09/09/25 | R 1 New England Revolution II 1 Huntsville City FC 0 G20:00 | 12/09/25 | R 1 New England Revolution II 2 Toronto FC II 1 G02:30 | 19/09/25 | R 1 New York City FC II 1 New England Revolution II 3 M01:00 | 22/09/25 | R 1 FC Cincinnati 2 3 New England Revolution II 1 M22:00 | 26/09/25 | R 1 New England Revolution II 0 Crown Legacy FC 1 G20:00 | 05/10/25 | R 1 Inter Miami CF II 2 New England Revolution II 5 |
| 5 | |  Chattanooga FC | 28 | 13 | 9 | 6 | 42 | 36 | 6 | 53 | G02:30 | 17/08/25 | R 1 Carolina Core FC 0 Chattanooga FC 1 G02:00 | 24/08/25 | R 1 Chattanooga FC 1 Huntsville City FC 0 G02:00 | 13/09/25 | R 1 Crown Legacy FC 2 Chattanooga FC 4 M22:00 | 21/09/25 | R 1 Chattanooga FC (5) 0 Carolina Core FC (6) 0 G02:30 | 29/09/25 | R 1 New York City FC II 0 Chattanooga FC 1 G20:00 | 05/10/25 | R 1 Chattanooga FC (5) 1 Atlanta United 2 (4) 1 |
| 6 | |  Huntsville City FC | 28 | 14 | 6 | 8 | 56 | 32 | 24 | 52 | M02:30 | 31/08/25 | R 1 Atlanta United 2 2 Huntsville City FC 0 M02:00 | 09/09/25 | R 1 New England Revolution II 1 Huntsville City FC 0 M03:00 | 14/09/25 | R 1 Huntsville City FC 2 New York Red Bulls II 3 G02:00 | 22/09/25 | R 1 Orlando City B 0 Huntsville City FC 1 G03:00 | 29/09/25 | R 1 Huntsville City FC 4 Inter Miami CF II 1 G20:00 | 05/10/25 | R 1 Huntsville City FC 3 Carolina Core FC 0 |
| 7 | |  San Jose Earthquakes II | 28 | 14 | 6 | 8 | 59 | 36 | 23 | 52 | G03:00 | 07/09/25 | R 1 San Jose Earthquakes II (4) 2 Portland Timbers II (3) 2 M23:00 | 13/09/25 | R 1 Vancouver Whitecaps FC II 3 San Jose Earthquakes II 1 G05:00 | 22/09/25 | R 1 Los Angeles Galaxy II 0 San Jose Earthquakes II 4 M01:00 | 29/09/25 | R 1 San Jose Earthquakes II 0 Tacoma Defiance 1 G05:00 | 02/10/25 | R 1 San Jose Earthquakes II 2 Vancouver Whitecaps FC II 1 M23:00 | 05/10/25 | R 1 San Jose Earthquakes II 1 Austin FC II 2 |
| 8 | |  Colorado Rapids 2 | 28 | 15 | 5 | 8 | 55 | 40 | 15 | 51 | G05:00 | 21/08/25 | R 1 Colorado Rapids 2 1 Portland Timbers II 0 G20:00 | 31/08/25 | R 1 Sporting Kansas City II 2 Colorado Rapids 2 3 M00:00 | 15/09/25 | R 1 Colorado Rapids 2 0 Houston Dynamo 2 1 G05:00 | 22/09/25 | R 1 Tacoma Defiance 1 Colorado Rapids 2 4 M23:30 | 27/09/25 | R 1 Colorado Rapids 2 1 Minnesota United FC 2 2 G23:00 | 05/10/25 | R 1 Los Angeles Galaxy II 0 Colorado Rapids 2 2 |
| 9 | |  Real Monarchs SLC | 28 | 13 | 8 | 7 | 55 | 42 | 13 | 51 | G04:30 | 01/09/25 | R 1 Real Monarchs SLC 3 Tacoma Defiance 0 M20:00 | 06/09/25 | R 1 Sporting Kansas City II 2 Real Monarchs SLC 1 G05:00 | 15/09/25 | R 1 Real Monarchs SLC 2 Los Angeles Galaxy II 1 G05:00 | 20/09/25 | R 1 Los Angeles FC 2 1 Real Monarchs SLC 3 G03:30 | 28/09/25 | R 1 North Texas SC 2 Real Monarchs SLC 4 G23:00 | 05/10/25 | R 1 Real Monarchs SLC 4 Vancouver Whitecaps FC II 1 |
| 10 | |  Chicago Fire FC II | 28 | 12 | 7 | 9 | 69 | 58 | 11 | 48 | G20:00 | 31/08/25 | R 1 New England Revolution II (1) 2 Chicago Fire FC II (3) 2 G22:00 | 10/09/25 | R 1 Chicago Fire FC II 2 FC Cincinnati 2 1 M05:00 | 15/09/25 | R 1 Chicago Fire FC II 4 New York City FC II 5 M22:00 | 21/09/25 | R 1 Philadelphia Union II 5 Chicago Fire FC II 2 M21:00 | 28/09/25 | R 1 Chicago Fire FC II 2 Atlanta United 2 5 G20:00 | 05/10/25 | R 1 Columbus Crew 2 (2) 3 Chicago Fire FC II (3) 3 |
| 11 | |  Minnesota United FC 2 | 28 | 12 | 6 | 10 | 45 | 42 | 3 | 44 | G03:00 | 01/09/25 | R 1 Minnesota United FC 2 1 San Jose Earthquakes II 0 G23:00 | 05/09/25 | R 1 Minnesota United FC 2 1 Austin FC II 0 M03:00 | 13/09/25 | R 1 Saint Louis City SC 2 (3) 1 Minnesota United FC 2 (2) 1 M23:00 | 21/09/25 | R 1 Minnesota United FC 2 1 North Texas SC 2 G23:30 | 27/09/25 | R 1 Colorado Rapids 2 1 Minnesota United FC 2 2 G23:00 | 05/10/25 | R 1 Minnesota United FC 2 3 Sporting Kansas City II 1 |
| 12 | |  North Texas SC | 28 | 11 | 6 | 11 | 46 | 56 | -10 | 43 | G05:00 | 01/09/25 | R 1 Los Angeles Galaxy II 0 North Texas SC 1 G03:30 | 07/09/25 | R 1 North Texas SC (5) 1 Los Angeles Galaxy II (4) 1 M03:30 | 15/09/25 | R 1 North Texas SC (3) 1 Sporting Kansas City II (4) 1 G23:00 | 21/09/25 | R 1 Minnesota United FC 2 1 North Texas SC 2 M03:30 | 28/09/25 | R 1 North Texas SC 2 Real Monarchs SLC 4 G23:00 | 05/10/25 | R 1 Los Angeles FC 2 2 North Texas SC 4 |
| 13 | |  Vancouver Whitecaps FC II | 28 | 11 | 5 | 12 | 61 | 54 | 7 | 42 | G02:00 | 01/09/25 | R 1 Vancouver Whitecaps FC II 4 Portland Timbers II 1 G05:00 | 05/09/25 | R 1 Tacoma Defiance 1 Vancouver Whitecaps FC II 3 G23:00 | 13/09/25 | R 1 Vancouver Whitecaps FC II 3 San Jose Earthquakes II 1 G02:00 | 20/09/25 | R 1 Sporting Kansas City II (2) 2 Vancouver Whitecaps FC II (4) 2 M05:00 | 02/10/25 | R 1 San Jose Earthquakes II 2 Vancouver Whitecaps FC II 1 M23:00 | 05/10/25 | R 1 Real Monarchs SLC 4 Vancouver Whitecaps FC II 1 |
| 14 | |  Los Angeles Galaxy II | 28 | 11 | 6 | 11 | 48 | 51 | -3 | 41 | M05:00 | 01/09/25 | R 1 Los Angeles Galaxy II 0 North Texas SC 1 M03:30 | 07/09/25 | R 1 North Texas SC (5) 1 Los Angeles Galaxy II (4) 1 M05:00 | 15/09/25 | R 1 Real Monarchs SLC 2 Los Angeles Galaxy II 1 M05:00 | 22/09/25 | R 1 Los Angeles Galaxy II 0 San Jose Earthquakes II 4 G20:00 | 28/09/25 | R 1 Sporting Kansas City II 1 Los Angeles Galaxy II 2 M23:00 | 05/10/25 | R 1 Los Angeles Galaxy II 0 Colorado Rapids 2 2 |
| 15 | |  Austin FC II | 28 | 10 | 8 | 10 | 35 | 36 | -1 | 41 | M05:00 | 30/08/25 | R 1 Los Angeles FC 2 1 Austin FC II 0 M23:00 | 05/09/25 | R 1 Minnesota United FC 2 1 Austin FC II 0 G05:00 | 13/09/25 | R 1 Tacoma Defiance 1 Austin FC II 2 M03:30 | 20/09/25 | R 1 Austin FC II 1 Saint Louis City SC 2 2 M03:30 | 27/09/25 | R 1 Austin FC II 1 Portland Timbers II 2 G23:00 | 05/10/25 | R 1 San Jose Earthquakes II 1 Austin FC II 2 |
| 16 | |  FC Cincinnati 2 | 28 | 9 | 7 | 12 | 40 | 41 | -1 | 41 | M02:30 | 01/09/25 | R 1 FC Cincinnati 2 1 Philadelphia Union II 2 M22:00 | 10/09/25 | R 1 Chicago Fire FC II 2 FC Cincinnati 2 1 G01:00 | 22/09/25 | R 1 FC Cincinnati 2 3 New England Revolution II 1 G02:30 | 26/09/25 | R 1 FC Cincinnati 2 4 Columbus Crew 2 3 G02:30 | 02/10/25 | R 1 FC Cincinnati 2 2 New York Red Bulls II 1 G20:00 | 05/10/25 | R 1 Orlando City B 1 FC Cincinnati 2 4 |
| 17 | |  Carolina Core FC | 28 | 8 | 10 | 10 | 42 | 44 | -2 | 39 | G18:00 | 24/08/25 | R 1 FC Cincinnati 2 2 Carolina Core FC 3 G02:00 | 05/09/25 | R 1 Crown Legacy FC 3 Carolina Core FC 4 G02:30 | 14/09/25 | R 1 Carolina Core FC 4 Atlanta United 2 2 G22:00 | 21/09/25 | R 1 Chattanooga FC (5) 0 Carolina Core FC (6) 0 M02:30 | 28/09/25 | R 1 Carolina Core FC (2) 3 Orlando City B (4) 3 M20:00 | 05/10/25 | R 1 Huntsville City FC 3 Carolina Core FC 0 |
| 18 | |  Portland Timbers II | 28 | 10 | 6 | 12 | 47 | 54 | -7 | 38 | M02:00 | 01/09/25 | R 1 Vancouver Whitecaps FC II 4 Portland Timbers II 1 M03:00 | 07/09/25 | R 1 San Jose Earthquakes II (4) 2 Portland Timbers II (3) 2 G23:00 | 14/09/25 | R 1 Portland Timbers II 5 Los Angeles FC 2 3 M03:00 | 22/09/25 | R 1 Houston Dynamo 2 3 Portland Timbers II 1 G03:30 | 27/09/25 | R 1 Austin FC II 1 Portland Timbers II 2 G23:00 | 05/10/25 | R 1 Portland Timbers II 2 Saint Louis City SC 2 1 |
| 19 | |  Toronto FC II | 28 | 10 | 6 | 12 | 34 | 42 | -8 | 38 | G02:00 | 21/08/25 | R 1 Philadelphia Union II (7) 2 Toronto FC II (8) 2 G22:00 | 31/08/25 | R 1 Toronto FC II 3 New York City FC II 0 M20:00 | 12/09/25 | R 1 New England Revolution II 2 Toronto FC II 1 G02:00 | 20/09/25 | R 1 Toronto FC II (4) 0 Columbus Crew 2 (3) 0 M02:00 | 27/09/25 | R 1 Toronto FC II 1 Philadelphia Union II 2 M20:00 | 05/10/25 | R 1 New York Red Bulls II 2 Toronto FC II 1 |
| 20 | |  Atlanta United 2 | 28 | 9 | 9 | 10 | 44 | 43 | 1 | 38 | M02:00 | 24/08/25 | R 1 Orlando City B 2 Atlanta United 2 1 G02:30 | 31/08/25 | R 1 Atlanta United 2 2 Huntsville City FC 0 M02:30 | 14/09/25 | R 1 Carolina Core FC 4 Atlanta United 2 2 G02:00 | 21/09/25 | R 1 Crown Legacy FC 0 Atlanta United 2 1 G21:00 | 28/09/25 | R 1 Chicago Fire FC II 2 Atlanta United 2 5 M20:00 | 05/10/25 | R 1 Chattanooga FC (5) 1 Atlanta United 2 (4) 1 |
| 21 | |  Houston Dynamo 2 | 28 | 9 | 6 | 13 | 40 | 47 | -7 | 37 | M03:00 | 23/08/25 | R 1 Houston Dynamo 2 0 San Jose Earthquakes II 1 G03:00 | 01/09/25 | R 1 Houston Dynamo 2 (4) 2 Saint Louis City SC 2 (3) 2 G00:00 | 15/09/25 | R 1 Colorado Rapids 2 0 Houston Dynamo 2 1 M03:00 | 18/09/25 | R 1 Houston Dynamo 2 1 Tacoma Defiance 2 G03:00 | 22/09/25 | R 1 Houston Dynamo 2 3 Portland Timbers II 1 M23:00 | 05/10/25 | R 1 Tacoma Defiance 5 Houston Dynamo 2 1 |
| 22 | |  Orlando City B | 28 | 9 | 6 | 13 | 38 | 55 | -17 | 37 | G02:00 | 24/08/25 | R 1 Orlando City B 2 Atlanta United 2 1 G02:00 | 01/09/25 | R 1 Orlando City B 1 Crown Legacy FC 0 G02:00 | 15/09/25 | R 1 Inter Miami CF II (3) 1 Orlando City B (5) 1 M02:00 | 22/09/25 | R 1 Orlando City B 0 Huntsville City FC 1 G02:30 | 28/09/25 | R 1 Carolina Core FC (2) 3 Orlando City B (4) 3 M20:00 | 05/10/25 | R 1 Orlando City B 1 FC Cincinnati 2 4 |
| 23 | |  Tacoma Defiance | 28 | 10 | 4 | 14 | 62 | 67 | -5 | 36 | M05:00 | 05/09/25 | R 1 Tacoma Defiance 1 Vancouver Whitecaps FC II 3 M05:00 | 13/09/25 | R 1 Tacoma Defiance 1 Austin FC II 2 G03:00 | 18/09/25 | R 1 Houston Dynamo 2 1 Tacoma Defiance 2 M05:00 | 22/09/25 | R 1 Tacoma Defiance 1 Colorado Rapids 2 4 G01:00 | 29/09/25 | R 1 San Jose Earthquakes II 0 Tacoma Defiance 1 G23:00 | 05/10/25 | R 1 Tacoma Defiance 5 Houston Dynamo 2 1 |
| 24 | |  New York City FC II | 28 | 9 | 6 | 13 | 53 | 61 | -8 | 35 | G02:30 | 23/08/25 | R 1 New York City FC II 3 Columbus Crew 2 1 M22:00 | 31/08/25 | R 1 Toronto FC II 3 New York City FC II 0 G05:00 | 15/09/25 | R 1 Chicago Fire FC II 4 New York City FC II 5 M02:30 | 19/09/25 | R 1 New York City FC II 1 New England Revolution II 3 M02:30 | 29/09/25 | R 1 New York City FC II 0 Chattanooga FC 1 M20:00 | 05/10/25 | R 1 Philadelphia Union II 4 New York City FC II 3 |
| 25 | |  Los Angeles FC 2 | 28 | 9 | 4 | 15 | 47 | 61 | -14 | 33 | G03:45 | 25/08/25 | R 1 North Texas SC 0 Los Angeles FC 2 4 G05:00 | 30/08/25 | R 1 Los Angeles FC 2 1 Austin FC II 0 M23:00 | 14/09/25 | R 1 Portland Timbers II 5 Los Angeles FC 2 3 M05:00 | 20/09/25 | R 1 Los Angeles FC 2 1 Real Monarchs SLC 3 M00:00 | 29/09/25 | R 1 Saint Louis City SC 2 (4) 1 Los Angeles FC 2 (2) 1 M23:00 | 05/10/25 | R 1 Los Angeles FC 2 2 North Texas SC 4 |
| 26 | |  Crown Legacy FC | 28 | 7 | 8 | 13 | 45 | 54 | -9 | 32 | G02:00 | 23/08/25 | R 1 Crown Legacy FC 6 Inter Miami CF II 0 M02:00 | 01/09/25 | R 1 Orlando City B 1 Crown Legacy FC 0 M02:00 | 05/09/25 | R 1 Crown Legacy FC 3 Carolina Core FC 4 M02:00 | 13/09/25 | R 1 Crown Legacy FC 2 Chattanooga FC 4 M02:00 | 21/09/25 | R 1 Crown Legacy FC 0 Atlanta United 2 1 G22:00 | 26/09/25 | R 1 New England Revolution II 0 Crown Legacy FC 1 |
| 27 | |  Inter Miami CF II | 28 | 6 | 6 | 16 | 40 | 72 | -32 | 25 | M02:00 | 23/08/25 | R 1 Crown Legacy FC 6 Inter Miami CF II 0 M22:00 | 07/09/25 | R 1 Columbus Crew 2 4 Inter Miami CF II 0 M02:00 | 15/09/25 | R 1 Inter Miami CF II (3) 1 Orlando City B (5) 1 G00:00 | 22/09/25 | R 1 New York Red Bulls II (2) 1 Inter Miami CF II (4) 1 M03:00 | 29/09/25 | R 1 Huntsville City FC 4 Inter Miami CF II 1 M20:00 | 05/10/25 | R 1 Inter Miami CF II 2 New England Revolution II 5 |
| 28 | |  Columbus Crew 2 | 28 | 5 | 6 | 17 | 40 | 64 | -24 | 22 | M02:00 | 01/09/25 | R 1 New York Red Bulls II 7 Columbus Crew 2 4 G22:00 | 07/09/25 | R 1 Columbus Crew 2 4 Inter Miami CF II 0 M22:00 | 14/09/25 | R 1 Columbus Crew 2 1 Philadelphia Union II 3 M02:00 | 20/09/25 | R 1 Toronto FC II (4) 0 Columbus Crew 2 (3) 0 M02:30 | 26/09/25 | R 1 FC Cincinnati 2 4 Columbus Crew 2 3 M20:00 | 05/10/25 | R 1 Columbus Crew 2 (2) 3 Chicago Fire FC II (3) 3 |
| 29 | |  Sporting Kansas City II | 28 | 3 | 6 | 19 | 30 | 67 | -37 | 17 | M20:00 | 31/08/25 | R 1 Sporting Kansas City II 2 Colorado Rapids 2 3 G20:00 | 06/09/25 | R 1 Sporting Kansas City II 2 Real Monarchs SLC 1 G03:30 | 15/09/25 | R 1 North Texas SC (3) 1 Sporting Kansas City II (4) 1 M02:00 | 20/09/25 | R 1 Sporting Kansas City II (2) 2 Vancouver Whitecaps FC II (4) 2 M20:00 | 28/09/25 | R 1 Sporting Kansas City II 1 Los Angeles Galaxy II 2 M23:00 | 05/10/25 | R 1 Minnesota United FC 2 3 Sporting Kansas City II 1 |
