| 1 | |  CF Pachucha | 17 | 12 | 2 | 3 | 30 | 15 | 15 | 38 | B03:00 | 12/05/22 | R quarterfinal  Atletico San Luis 2 CF Pachucha 2 G04:05 | 15/05/22 | R quarterfinal CF Pachucha 3 Atletico San Luis 2 B04:00 | 20/05/22 | R semifinal CF America 1 CF Pachucha 1 G04:06 | 23/05/22 | R semifinal CF Pachucha 3 CF America 0 M05:00 | 27/05/22 | R final Atlas FC 2 CF Pachucha 0 G04:10 | 30/05/22 | R final CF Pachucha 2 Atlas FC 1 |
| 2 | |  Tigres UANL | 17 | 10 | 3 | 4 | 30 | 20 | 10 | 33 | M03:00 | 24/04/22 | R 16 Tigres UANL 0 CF America 2 B03:00 | 01/05/22 | R 17 Atlas FC 1 Tigres UANL 1 G03:00 | 13/05/22 | R quarterfinal Cruz Azul 0 Tigres UANL 1 M04:05 | 16/05/22 | R quarterfinal Tigres UANL 0 Cruz Azul 1 M05:00 | 19/05/22 | R semifinal Atlas FC 3 Tigres UANL 0 M04:00 | 22/05/22 | R semifinal Tigres UANL 0 Atlas FC 2 |
| 3 | |  Atlas FC | 17 | 7 | 6 | 4 | 21 | 15 | 6 | 27 | G05:05 | 13/05/22 | R quarterfinal Guadalajara Chivas 1 Atlas FC 2 B02:00 | 16/05/22 | R quarterfinal Atlas FC 1 Guadalajara Chivas 1 G05:00 | 19/05/22 | R semifinal Atlas FC 3 Tigres UANL 0 G04:00 | 22/05/22 | R semifinal Tigres UANL 0 Atlas FC 2 G05:00 | 27/05/22 | R final Atlas FC 2 CF Pachucha 0 M04:10 | 30/05/22 | R final CF Pachucha 2 Atlas FC 1 |
| 4 | |  CF America | 17 | 7 | 5 | 5 | 24 | 17 | 7 | 26 | G03:00 | 24/04/22 | R 16 Tigres UANL 0 CF America 2 B05:00 | 01/05/22 | R 17 CF America 0 Cruz Azul 0 B05:05 | 12/05/22 | R quarterfinal Puebla FC 1 CF America 1 G02:00 | 15/05/22 | R quarterfinal CF America 3 Puebla FC 2 B04:00 | 20/05/22 | R semifinal CF America 1 CF Pachucha 1 M04:06 | 23/05/22 | R semifinal CF Pachucha 3 CF America 0 |
| 5 | |  Puebla FC | 17 | 7 | 5 | 5 | 25 | 19 | 6 | 26 | M03:00 | 20/04/22 | R 15 CF Pachucha 1 Puebla FC 0 M03:00 | 23/04/22 | R 16 Puebla FC 0 Necaxa 1 M05:05 | 30/04/22 | R 17 Mazatlan FC 2 Puebla FC 1 G01:00 | 09/05/22 | R 1 Puebla FC (3) 2 Mazatlan FC (1) 2 B05:05 | 12/05/22 | R quarterfinal Puebla FC 1 CF America 1 M02:00 | 15/05/22 | R quarterfinal CF America 3 Puebla FC 2 |
| 6 | |  Guadalajara Chivas | 17 | 7 | 5 | 5 | 25 | 21 | 4 | 26 | G05:00 | 20/04/22 | R 15 Guadalajara Chivas 2 Club Tijuana de Caliente 1 G05:00 | 24/04/22 | R 16 Guadalajara Chivas 3 Pumas Unam 1 G03:00 | 30/04/22 | R 17 Necaxa 0 Guadalajara Chivas 1 G03:15 | 09/05/22 | R 1 Guadalajara Chivas 4 Pumas Unam 1 M05:05 | 13/05/22 | R quarterfinal Guadalajara Chivas 1 Atlas FC 2 B02:00 | 16/05/22 | R quarterfinal Atlas FC 1 Guadalajara Chivas 1 |
| 7 | |  CF Monterrey | 17 | 7 | 5 | 5 | 21 | 17 | 4 | 26 | M20:00 | 17/04/22 | R 14 Pumas Unam 2 CF Monterrey 0 B05:06 | 21/04/22 | R 15 CF Monterrey 0 Atlas FC 0 M01:00 | 24/04/22 | R 16 CF Pachucha 3 CF Monterrey 0 G03:06 | 01/05/22 | R 17 CF Monterrey 2 Club Tijuana de Caliente 0 M04:00 | 08/05/22 | R 1 CF Monterrey (1) 2 Atletico San Luis (3) 2 B04:00 | 08/05/22 | R 1 CF Monterrey (0) 2 Atletico San Luis (0) 2 |
| 8 | |  Cruz Azul | 17 | 7 | 4 | 6 | 20 | 17 | 3 | 25 | M01:00 | 25/04/22 | R 16 Cruz Azul 0 Atletico San Luis 1 B05:00 | 01/05/22 | R 17 CF America 0 Cruz Azul 0 G01:45 | 08/05/22 | R 1 Cruz Azul (3) 1 Necaxa (1) 1 B01:45 | 08/05/22 | R 1 Cruz Azul (0) 1 Necaxa (0) 1 M03:00 | 13/05/22 | R quarterfinal Cruz Azul 0 Tigres UANL 1 G04:05 | 16/05/22 | R quarterfinal Tigres UANL 0 Cruz Azul 1 |
| 9 | |  Necaxa | 17 | 7 | 2 | 8 | 21 | 21 | 0 | 23 | G03:00 | 16/04/22 | R 14 Necaxa 4 Atletico San Luis 2 G03:00 | 20/04/22 | R 15 Necaxa 2 Tigres UANL 0 G03:00 | 23/04/22 | R 16 Puebla FC 0 Necaxa 1 M03:00 | 30/04/22 | R 17 Necaxa 0 Guadalajara Chivas 1 M01:45 | 08/05/22 | R 1 Cruz Azul (3) 1 Necaxa (1) 1 B01:45 | 08/05/22 | R 1 Cruz Azul (0) 1 Necaxa (0) 1 |
| 10 | |  Atletico San Luis | 17 | 7 | 2 | 8 | 21 | 22 | -1 | 23 | G01:00 | 25/04/22 | R 16 Cruz Azul 0 Atletico San Luis 1 M00:00 | 02/05/22 | R 17 Atletico San Luis 1 Club Santos Laguna 3 G04:00 | 08/05/22 | R 1 CF Monterrey (1) 2 Atletico San Luis (3) 2 B04:00 | 08/05/22 | R 1 CF Monterrey (0) 2 Atletico San Luis (0) 2 B03:00 | 12/05/22 | R quarterfinal Atletico San Luis 2 CF Pachucha 2 M04:05 | 15/05/22 | R quarterfinal CF Pachucha 3 Atletico San Luis 2 |
| 11 | |  Pumas Unam | 17 | 6 | 4 | 7 | 24 | 21 | 3 | 22 | B03:00 | 09/04/22 | R 13 Puebla FC 2 Pumas Unam 2 G20:00 | 17/04/22 | R 14 Pumas Unam 2 CF Monterrey 0 M03:00 | 21/04/22 | R 15 Atletico San Luis 2 Pumas Unam 0 M05:00 | 24/04/22 | R 16 Guadalajara Chivas 3 Pumas Unam 1 G20:00 | 01/05/22 | R 17 Pumas Unam 2 CF Pachucha 0 M03:15 | 09/05/22 | R 1 Guadalajara Chivas 4 Pumas Unam 1 |
| 12 | |  Mazatlan FC | 17 | 6 | 3 | 8 | 20 | 24 | -4 | 21 | B05:00 | 09/04/22 | R 13 Mazatlan FC 1 Cruz Azul 1 G05:00 | 15/04/22 | R 14 Atlas FC 1 Mazatlan FC 2 G05:00 | 20/04/22 | R 15 Mazatlan FC 1 Club Santos Laguna 0 G05:00 | 23/04/22 | R 16 FC Juarez 0 Mazatlan FC 2 G05:05 | 30/04/22 | R 17 Mazatlan FC 2 Puebla FC 1 M01:00 | 09/05/22 | R 1 Puebla FC (3) 2 Mazatlan FC (1) 2 |
| 13 | |  Club Leon | 17 | 5 | 6 | 6 | 17 | 22 | -5 | 21 | B01:00 | 04/04/22 | R 12 Club Leon 1 Queretaro FC 1 M01:00 | 10/04/22 | R 13 Atletico San Luis 2 Club Leon 0 M01:00 | 17/04/22 | R 14 Club Leon 0 Puebla FC 1 M05:00 | 21/04/22 | R 15 CF America 2 Club Leon 0 B03:00 | 25/04/22 | R 16 Club Santos Laguna 1 Club Leon 1 B04:06 | 02/05/22 | R 17 Club Leon 4 Deportivo Toluca FC 4 |
| 14 | |  Club Santos Laguna | 17 | 5 | 5 | 7 | 25 | 25 | 0 | 20 | G03:00 | 04/04/22 | R 12 Club Santos Laguna 3 CF Pachucha 1 M03:06 | 10/04/22 | R 13 CF Monterrey 1 Club Santos Laguna 0 B03:00 | 17/04/22 | R 14 Club Santos Laguna 1 Queretaro FC 1 M05:00 | 20/04/22 | R 15 Mazatlan FC 1 Club Santos Laguna 0 B03:00 | 25/04/22 | R 16 Club Santos Laguna 1 Club Leon 1 G00:00 | 02/05/22 | R 17 Atletico San Luis 1 Club Santos Laguna 3 |
| 15 | |  Deportivo Toluca FC | 17 | 5 | 4 | 8 | 21 | 36 | -15 | 19 | B03:00 | 07/04/22 | R 4 Deportivo Toluca FC 2 CF Monterrey 2 B03:00 | 10/04/22 | R 13 Deportivo Toluca FC 1 Guadalajara Chivas 1 M03:00 | 17/04/22 | R 14 Tigres UANL 3 Deportivo Toluca FC 0 M05:00 | 20/04/22 | R 15 Deportivo Toluca FC 0 FC Juarez 1 M20:00 | 24/04/22 | R 16 Deportivo Toluca FC 2 Atlas FC 4 B04:06 | 02/05/22 | R 17 Club Leon 4 Deportivo Toluca FC 4 |
| 16 | |  Queretaro FC | 17 | 3 | 8 | 6 | 18 | 21 | -3 | 17 | B01:00 | 04/04/22 | R 12 Club Leon 1 Queretaro FC 1 M03:00 | 11/04/22 | R 13 Queretaro FC 0 Tigres UANL 1 B03:00 | 17/04/22 | R 14 Club Santos Laguna 1 Queretaro FC 1 M05:00 | 22/04/22 | R 15 Queretaro FC 0 Cruz Azul 1 B05:06 | 25/04/22 | R 16 Club Tijuana de Caliente 2 Queretaro FC 2 G01:00 | 01/05/22 | R 17 Queretaro FC 4 FC Juarez 0 |
| 17 | |  Club Tijuana de Caliente | 17 | 4 | 5 | 8 | 14 | 26 | -12 | 17 | B05:06 | 07/04/22 | R 9 Club Tijuana de Caliente 1 Atletico San Luis 1 B05:00 | 12/04/22 | R 13 CF Pachucha 0 Club Tijuana de Caliente 0 M05:06 | 16/04/22 | R 14 Club Tijuana de Caliente 1 CF America 3 M05:00 | 20/04/22 | R 15 Guadalajara Chivas 2 Club Tijuana de Caliente 1 B05:06 | 25/04/22 | R 16 Club Tijuana de Caliente 2 Queretaro FC 2 M03:06 | 01/05/22 | R 17 CF Monterrey 2 Club Tijuana de Caliente 0 |
| 18 | |  FC Juarez | 17 | 3 | 2 | 12 | 10 | 28 | -18 | 11 | M06:00 | 03/04/22 | R 12 FC Juarez 0 Pumas Unam 1 M05:00 | 10/04/22 | R 13 CF America 3 FC Juarez 0 M05:00 | 16/04/22 | R 14 FC Juarez 1 CF Pachucha 2 G05:00 | 20/04/22 | R 15 Deportivo Toluca FC 0 FC Juarez 1 M05:00 | 23/04/22 | R 16 FC Juarez 0 Mazatlan FC 2 M01:00 | 01/05/22 | R 17 Queretaro FC 4 FC Juarez 0 |
