| 1 | |  Galatasaray | 38 | 27 | 5 | 6 | 81 | 37 | 44 | 86 | G19:00 | 18/05/22 | R 28  Fenerbahçe 1 Galatasaray 2 M14:00 | 22/05/22 | R 35 Antalyaspor 2 Galatasaray 1 G13:00 | 25/05/22 | R 24 Galatasaray 4 Beşiktas JK 1 B15:00 | 28/05/22 | R 36 Çaykur Rizespor 1 Galatasaray 1 G13:00 | 01/06/22 | R 37 Galatasaray 2 Konyaspor 1 M16:00 | 04/06/22 | R 38 Beşiktas JK 2 Galatasaray 0 |
| 2 | |  Beşiktas JK | 38 | 25 | 8 | 5 | 88 | 39 | 49 | 83 | G14:00 | 15/05/22 | R 34 Göztepe 1 Beşiktas JK 6 G13:00 | 21/05/22 | R 35 Beşiktas JK 3 Konyaspor 2 M13:00 | 25/05/22 | R 24 Galatasaray 4 Beşiktas JK 1 G15:00 | 28/05/22 | R 36 Beşiktas JK 3 Sivasspor 1 B16:00 | 01/06/22 | R 37 İstanbul Başakşehir FK 3 Beşiktas JK 3 G16:00 | 04/06/22 | R 38 Beşiktas JK 2 Galatasaray 0 |
| 3 | |  Trabzonspor | 38 | 24 | 9 | 5 | 83 | 33 | 50 | 81 | G12:00 | 11/05/22 | R 20 Trabzonspor 2 Galatasaray 1 G12:00 | 17/05/22 | R 34 Trabzonspor 4 Altay 0 G12:00 | 22/05/22 | R 35 İstanbul Başakşehir FK 1 Trabzonspor 4 G15:00 | 28/05/22 | R 36 Mondihome Kayserispor 1 Trabzonspor 2 G16:00 | 01/06/22 | R 37 Trabzonspor 2 Fenerbahçe 0 G12:00 | 04/06/22 | R 38 Göztepe 0 Trabzonspor 1 |
| 4 | |  Fenerbahçe | 38 | 23 | 9 | 6 | 75 | 39 | 36 | 78 | M19:00 | 18/05/22 | R 28 Fenerbahçe 1 Galatasaray 2 G12:00 | 21/05/22 | R 35 Yeni Malatyaspor 1 Fenerbahçe 2 G14:00 | 25/05/22 | R 20 Fenerbahçe 2 Sivasspor 0 B15:00 | 28/05/22 | R 36 Fenerbahçe 1 Kasımpaşa 1 M16:00 | 01/06/22 | R 37 Trabzonspor 2 Fenerbahçe 0 G13:00 | 04/06/22 | R 38 Fenerbahçe 4 Aytemiz Alanyaspor 0 |
| 5 | |  Sivasspor | 38 | 21 | 5 | 12 | 74 | 45 | 29 | 68 | M12:00 | 16/05/22 | R 34 Çaykur Rizespor 5 Sivasspor 2 G14:30 | 20/05/22 | R 35 Sivasspor 3 Mondihome Kayserispor 0 M14:00 | 25/05/22 | R 20 Fenerbahçe 2 Sivasspor 0 M15:00 | 28/05/22 | R 36 Beşiktas JK 3 Sivasspor 1 G14:00 | 01/06/22 | R 37 Sivasspor 5 Antalyaspor 0 G16:00 | 04/06/22 | R 38 Sivasspor 2 Adana Demirspor 1 |
| 6 | |  Konyaspor | 38 | 19 | 11 | 8 | 60 | 35 | 25 | 68 | G12:00 | 11/05/22 | R 24 Mondihome Kayserispor 0 Konyaspor 3 G12:00 | 15/05/22 | R 34 Konyaspor 2 Atakaş Hatayspor 1 M13:00 | 21/05/22 | R 35 Beşiktas JK 3 Konyaspor 2 G13:00 | 28/05/22 | R 36 Konyaspor 1 Aytemiz Alanyaspor 0 M13:00 | 01/06/22 | R 37 Galatasaray 2 Konyaspor 1 G16:00 | 04/06/22 | R 38 Konyaspor 5 Mondihome Kayserispor 4 |
| 7 | |  Antalyaspor | 38 | 20 | 5 | 13 | 73 | 71 | 2 | 65 | M12:00 | 08/05/22 | R 33 Antalyaspor 1 Konyaspor 4 G12:00 | 15/05/22 | R 34 Kasımpaşa 0 Antalyaspor 3 G14:00 | 22/05/22 | R 35 Antalyaspor 2 Galatasaray 1 B15:00 | 28/05/22 | R 36 Antalyaspor 1 Adana Demirspor 1 M14:00 | 01/06/22 | R 37 Sivasspor 5 Antalyaspor 0 G16:00 | 04/06/22 | R 38 Antalyaspor 3 İstanbul Başakşehir FK 0 |
| 8 | |  Aytemiz Alanyaspor | 38 | 15 | 9 | 14 | 51 | 47 | 4 | 54 | M16:00 | 11/05/22 | R 24 Aytemiz Alanyaspor 1 Fenerbahçe 2 B16:00 | 15/05/22 | R 34 Aytemiz Alanyaspor 1 Gazişehir Gaziantep FK 1 G12:00 | 22/05/22 | R 35 Vavacars Karagümrük 0 Aytemiz Alanyaspor 1 M13:00 | 28/05/22 | R 36 Konyaspor 1 Aytemiz Alanyaspor 0 G16:00 | 01/06/22 | R 37 Aytemiz Alanyaspor 4 Mondihome Kayserispor 2 M13:00 | 04/06/22 | R 38 Fenerbahçe 4 Aytemiz Alanyaspor 0 |
| 9 | |  Çaykur Rizespor | 38 | 15 | 9 | 14 | 58 | 62 | -4 | 54 | M12:00 | 08/05/22 | R 33 Yeni Malatyaspor 4 Çaykur Rizespor 1 G12:00 | 16/05/22 | R 34 Çaykur Rizespor 5 Sivasspor 2 M12:00 | 20/05/22 | R 35 Gazişehir Gaziantep FK 3 Çaykur Rizespor 0 B15:00 | 28/05/22 | R 36 Çaykur Rizespor 1 Galatasaray 1 G16:00 | 01/06/22 | R 37 Giresunspor 1 Çaykur Rizespor 4 G16:00 | 04/06/22 | R 38 Çaykur Rizespor 3 Kasımpaşa 2 |
| 10 | |  Kasımpaşa | 38 | 12 | 13 | 13 | 47 | 48 | -1 | 49 | B12:00 | 07/05/22 | R 33 Sivasspor 1 Kasımpaşa 1 M12:00 | 15/05/22 | R 34 Kasımpaşa 0 Antalyaspor 3 G12:00 | 21/05/22 | R 35 Altay 0 Kasımpaşa 1 B15:00 | 28/05/22 | R 36 Fenerbahçe 1 Kasımpaşa 1 B17:00 | 01/06/22 | R 37 Kasımpaşa 2 Göztepe 2 M16:00 | 04/06/22 | R 38 Çaykur Rizespor 3 Kasımpaşa 2 |
| 11 | |  İstanbul Başakşehir FK | 38 | 11 | 13 | 14 | 45 | 61 | -16 | 46 | G14:00 | 15/05/22 | R 34 Giresunspor 0 İstanbul Başakşehir FK 1 M12:00 | 22/05/22 | R 35 İstanbul Başakşehir FK 1 Trabzonspor 4 G13:00 | 25/05/22 | R 16 İstanbul Başakşehir FK 3 Mondihome Kayserispor 2 B16:00 | 28/05/22 | R 36 Vavacars Karagümrük 3 İstanbul Başakşehir FK 3 B16:00 | 01/06/22 | R 37 İstanbul Başakşehir FK 3 Beşiktas JK 3 M16:00 | 04/06/22 | R 38 Antalyaspor 3 İstanbul Başakşehir FK 0 |
| 12 | |  Adana Demirspor | 38 | 10 | 13 | 15 | 46 | 50 | -4 | 43 | B17:00 | 07/05/22 | R 33 Adana Demirspor 0 Aytemiz Alanyaspor 0 M12:00 | 14/05/22 | R 34 Galatasaray 1 Adana Demirspor 0 G15:00 | 22/05/22 | R 35 Adana Demirspor 2 Göztepe 1 B15:00 | 28/05/22 | R 36 Antalyaspor 1 Adana Demirspor 1 G17:00 | 01/06/22 | R 37 Adana Demirspor 2 Yeni Malatyaspor 1 M16:00 | 04/06/22 | R 38 Sivasspor 2 Adana Demirspor 1 |
| 13 | |  Gazişehir Gaziantep FK | 38 | 11 | 9 | 18 | 44 | 55 | -11 | 42 | M14:00 | 07/05/22 | R 33 Gazişehir Gaziantep FK 0 Mondihome Kayserispor 1 B16:00 | 15/05/22 | R 34 Aytemiz Alanyaspor 1 Gazişehir Gaziantep FK 1 G12:00 | 20/05/22 | R 35 Gazişehir Gaziantep FK 3 Çaykur Rizespor 0 M15:00 | 28/05/22 | R 36 Gazişehir Gaziantep FK 3 Altay 4 B16:00 | 01/06/22 | R 37 Atakaş Hatayspor 0 Gazişehir Gaziantep FK 0 G14:00 | 04/06/22 | R 38 Gazişehir Gaziantep FK 4 Giresunspor 1 |
| 14 | |  Vavacars Karagümrük | 38 | 11 | 7 | 20 | 56 | 67 | -11 | 40 | M12:00 | 11/05/22 | R 31 Sivasspor 4 Vavacars Karagümrük 2 B14:00 | 15/05/22 | R 34 Fenerbahçe 0 Vavacars Karagümrük 0 M12:00 | 22/05/22 | R 35 Vavacars Karagümrük 0 Aytemiz Alanyaspor 1 B16:00 | 28/05/22 | R 36 Vavacars Karagümrük 3 İstanbul Başakşehir FK 3 B16:00 | 01/06/22 | R 37 Altay 0 Vavacars Karagümrük 0 G15:00 | 04/06/22 | R 38 Vavacars Karagümrük 5 Atakaş Hatayspor 1 |
| 15 | |  Mondihome Kayserispor | 38 | 10 | 9 | 19 | 60 | 78 | -18 | 39 | G12:00 | 14/05/22 | R 34 Mondihome Kayserispor 3 Yeni Malatyaspor 0 M14:30 | 20/05/22 | R 35 Sivasspor 3 Mondihome Kayserispor 0 M13:00 | 25/05/22 | R 16 İstanbul Başakşehir FK 3 Mondihome Kayserispor 2 M15:00 | 28/05/22 | R 36 Mondihome Kayserispor 1 Trabzonspor 2 M16:00 | 01/06/22 | R 37 Aytemiz Alanyaspor 4 Mondihome Kayserispor 2 M16:00 | 04/06/22 | R 38 Konyaspor 5 Mondihome Kayserispor 4 |
| 16 | |  Altay | 38 | 10 | 8 | 20 | 46 | 75 | -29 | 38 | M12:00 | 11/05/22 | R 19 Beşiktas JK 5 Altay 1 M12:00 | 17/05/22 | R 34 Trabzonspor 4 Altay 0 M12:00 | 21/05/22 | R 35 Altay 0 Kasımpaşa 1 G15:00 | 28/05/22 | R 36 Gazişehir Gaziantep FK 3 Altay 4 B16:00 | 01/06/22 | R 37 Altay 0 Vavacars Karagümrük 0 G16:00 | 04/06/22 | R 38 Yeni Malatyaspor 0 Altay 3 |
| 17 | |  Göztepe | 38 | 9 | 10 | 19 | 44 | 69 | -25 | 37 | M14:00 | 15/05/22 | R 34 Göztepe 1 Beşiktas JK 6 M15:00 | 22/05/22 | R 35 Adana Demirspor 2 Göztepe 1 B12:00 | 25/05/22 | R 26 Göztepe 1 Atakaş Hatayspor 1 G12:00 | 28/05/22 | R 36 Göztepe 4 Giresunspor 0 B17:00 | 01/06/22 | R 37 Kasımpaşa 2 Göztepe 2 M12:00 | 04/06/22 | R 38 Göztepe 0 Trabzonspor 1 |
| 18 | |  Yeni Malatyaspor | 38 | 9 | 7 | 22 | 31 | 67 | -36 | 34 | G12:00 | 08/05/22 | R 33 Yeni Malatyaspor 4 Çaykur Rizespor 1 M12:00 | 14/05/22 | R 34 Mondihome Kayserispor 3 Yeni Malatyaspor 0 M12:00 | 21/05/22 | R 35 Yeni Malatyaspor 1 Fenerbahçe 2 M15:00 | 28/05/22 | R 36 Yeni Malatyaspor 1 Atakaş Hatayspor 2 M17:00 | 01/06/22 | R 37 Adana Demirspor 2 Yeni Malatyaspor 1 M16:00 | 04/06/22 | R 38 Yeni Malatyaspor 0 Altay 3 |
| 19 | |  Atakaş Hatayspor | 38 | 8 | 8 | 22 | 50 | 69 | -19 | 32 | M12:00 | 15/05/22 | R 34 Konyaspor 2 Atakaş Hatayspor 1 G14:00 | 22/05/22 | R 35 Atakaş Hatayspor 5 Giresunspor 1 B12:00 | 25/05/22 | R 26 Göztepe 1 Atakaş Hatayspor 1 G15:00 | 28/05/22 | R 36 Yeni Malatyaspor 1 Atakaş Hatayspor 2 B16:00 | 01/06/22 | R 37 Atakaş Hatayspor 0 Gazişehir Gaziantep FK 0 M15:00 | 04/06/22 | R 38 Vavacars Karagümrük 5 Atakaş Hatayspor 1 |
| 20 | |  Giresunspor | 38 | 1 | 11 | 26 | 29 | 94 | -65 | 14 | M12:00 | 08/05/22 | R 33 Altay 3 Giresunspor 0 M14:00 | 15/05/22 | R 34 Giresunspor 0 İstanbul Başakşehir FK 1 M14:00 | 22/05/22 | R 35 Atakaş Hatayspor 5 Giresunspor 1 M12:00 | 28/05/22 | R 36 Göztepe 4 Giresunspor 0 M16:00 | 01/06/22 | R 37 Giresunspor 1 Çaykur Rizespor 4 M14:00 | 04/06/22 | R 38 Gazişehir Gaziantep FK 4 Giresunspor 1 |
