| 1 | |  Tigres UANL | 12 | 10 | 1 | 1 | 25 | 10 | 15 | 31 | M20:00 | 05/09/25 | R 7  Santos Laguna 1 Tigres UANL 0 G18:00 | 13/09/25 | R 8 Tigres UANL 2 Club Leon U21 1 G18:00 | 17/09/25 | R 1 Guadalajara U21 1 Tigres UANL 2 G18:00 | 20/09/25 | R 9 Universidad Nacional U21 1 Tigres UANL 5 G18:00 | 28/09/25 | R 11 Gallos Blancos de Queretaro 0 Tigres UANL 1 G18:00 | 04/10/25 | R 12 Tigres UANL 1 Cruz Azul 0 |
| 2 | |  Pachuca U21 | 12 | 9 | 2 | 1 | 33 | 10 | 23 | 30 | B18:00 | 30/08/25 | R 7 Club America 0 Pachuca U21 0 G18:15 | 13/09/25 | R 8 Pachuca U21 5 Cruz Azul 0 G18:15 | 20/09/25 | R 9 Pachuca U21 (4) 1 Gallos Blancos de Queretaro (3) 1 G18:00 | 23/09/25 | R 10 Puebla U21 0 Pachuca U21 4 M18:15 | 27/09/25 | R 11 Pachuca U21 2 Atletico San Luis 3 G18:00 | 03/10/25 | R 12 Necaxa U21 1 Pachuca U21 2 |
| 3 | |  Necaxa U21 | 12 | 4 | 5 | 3 | 32 | 23 | 9 | 22 | G02:45 | 01/09/25 | R 7 Club Tijuana de Caliente (5) 2 Necaxa U21 (6) 2 G18:00 | 12/09/25 | R 8 Necaxa U21 (5) 0 FC Juarez U21 (4) 0 M18:00 | 19/09/25 | R 9 Necaxa U21 0 Puebla U21 1 G18:00 | 23/09/25 | R 10 Guadalajara U21 0 Necaxa U21 2 G18:00 | 27/09/25 | R 11 Atlas FC 1 Necaxa U21 2 M18:00 | 03/10/25 | R 12 Necaxa U21 1 Pachuca U21 2 |
| 4 | |  Deportivo Toluca FC | 12 | 4 | 5 | 3 | 27 | 23 | 4 | 19 | M18:00 | 16/08/25 | R 5 Deportivo Toluca FC 1 Universidad Nacional U21 2 M18:00 | 23/08/25 | R 6 Cruz Azul (5) 0 Deportivo Toluca FC (4) 0 G18:00 | 29/08/25 | R 7 Atletico San Luis 0 Deportivo Toluca FC 2 M18:00 | 20/09/25 | R 9 Guadalajara U21 1 Deportivo Toluca FC 0 G18:00 | 27/09/25 | R 11 Deportivo Toluca FC 4 Mazatlan FC U21 1 G18:00 | 04/10/25 | R 12 Club Leon U21 (3) 2 Deportivo Toluca FC (4) 2 |
| 5 | |  Club Tijuana de Caliente | 12 | 6 | 1 | 5 | 22 | 21 | 1 | 19 | G02:45 | 23/08/25 | R 6 Club Tijuana de Caliente 1 Guadalajara U21 0 M02:45 | 01/09/25 | R 7 Club Tijuana de Caliente (5) 2 Necaxa U21 (6) 2 G18:00 | 14/09/25 | R 8 Atletico San Luis 0 Club Tijuana de Caliente 2 M02:45 | 20/09/25 | R 9 Club Tijuana de Caliente 0 Club Leon U21 1 G01:45 | 29/09/25 | R 11 Club Tijuana de Caliente 2 Cruz Azul 1 G02:45 | 06/10/25 | R 12 Club Tijuana de Caliente 3 CF Monterrey 1 |
| 6 | |  Universidad Nacional U21 | 12 | 6 | 1 | 5 | 18 | 24 | -6 | 19 | G18:00 | 31/08/25 | R 7 Universidad Nacional U21 2 Atlas FC 1 G19:00 | 12/09/25 | R 8 Mazatlan FC U21 0 Universidad Nacional U21 1 M18:00 | 20/09/25 | R 9 Universidad Nacional U21 1 Tigres UANL 5 M18:00 | 23/09/25 | R 10 FC Juarez U21 3 Universidad Nacional U21 0 G18:00 | 27/09/25 | R 11 Club America 0 Universidad Nacional U21 1 M18:00 | 05/10/25 | R 12 Universidad Nacional U21 (2) 2 Guadalajara U21 (4) 2 |
| 7 | |  Puebla U21 | 12 | 4 | 4 | 4 | 18 | 18 | 0 | 18 | G18:00 | 24/08/25 | R 6 Universidad Nacional U21 1 Puebla U21 2 G18:00 | 29/08/25 | R 7 Puebla U21 (4) 2 CF Monterrey (2) 2 G18:00 | 19/09/25 | R 9 Necaxa U21 0 Puebla U21 1 M18:00 | 23/09/25 | R 10 Puebla U21 0 Pachuca U21 4 B18:00 | 26/09/25 | R 11 Puebla U21 1 Guadalajara U21 1 M18:00 | 04/10/25 | R 12 Gallos Blancos de Queretaro 2 Puebla U21 0 |
| 8 | |  Club America | 12 | 4 | 5 | 3 | 24 | 27 | -3 | 18 | M18:00 | 24/08/25 | R 6 Atlas FC 1 Club America 0 B18:00 | 30/08/25 | R 7 Club America 0 Pachuca U21 0 M18:00 | 13/09/25 | R 8 Club America (2) 1 Guadalajara U21 (3) 1 M18:00 | 20/09/25 | R 9 CF Monterrey (7) 2 Club America (6) 2 M18:00 | 27/09/25 | R 11 Club America 0 Universidad Nacional U21 1 G18:00 | 04/10/25 | R 12 Club America 1 Santos Laguna 0 |
| 9 | |  Guadalajara U21 | 12 | 4 | 3 | 5 | 22 | 21 | 1 | 17 | G18:00 | 13/09/25 | R 8 Club America (2) 1 Guadalajara U21 (3) 1 M18:00 | 17/09/25 | R 1 Guadalajara U21 1 Tigres UANL 2 G18:00 | 20/09/25 | R 9 Guadalajara U21 1 Deportivo Toluca FC 0 M18:00 | 23/09/25 | R 10 Guadalajara U21 0 Necaxa U21 2 B18:00 | 26/09/25 | R 11 Puebla U21 1 Guadalajara U21 1 G18:00 | 05/10/25 | R 12 Universidad Nacional U21 (2) 2 Guadalajara U21 (4) 2 |
| 10 | |  Cruz Azul | 12 | 4 | 3 | 5 | 23 | 24 | -1 | 17 | G18:00 | 23/08/25 | R 6 Cruz Azul (5) 0 Deportivo Toluca FC (4) 0 G18:00 | 30/08/25 | R 7 Guadalajara U21 2 Cruz Azul 4 M18:15 | 13/09/25 | R 8 Pachuca U21 5 Cruz Azul 0 M18:00 | 19/09/25 | R 9 Cruz Azul 0 FC Juarez U21 1 M01:45 | 29/09/25 | R 11 Club Tijuana de Caliente 2 Cruz Azul 1 M18:00 | 04/10/25 | R 12 Tigres UANL 1 Cruz Azul 0 |
| 11 | |  Santos Laguna | 12 | 5 | 2 | 5 | 18 | 19 | -1 | 17 | M18:00 | 22/08/25 | R 6 FC Juarez U21 2 Santos Laguna 0 G20:00 | 05/09/25 | R 7 Santos Laguna 1 Tigres UANL 0 M18:00 | 13/09/25 | R 8 Atlas FC (3) 1 Santos Laguna (2) 1 G20:00 | 21/09/25 | R 9 Santos Laguna 3 Atletico San Luis 1 G18:00 | 27/09/25 | R 11 CF Monterrey 2 Santos Laguna 3 M18:00 | 04/10/25 | R 12 Club America 1 Santos Laguna 0 |
| 12 | |  Club Leon U21 | 12 | 3 | 4 | 5 | 33 | 30 | 3 | 16 | G18:00 | 30/08/25 | R 7 Club Leon U21 (5) 2 Gallos Blancos de Queretaro (4) 2 M18:00 | 13/09/25 | R 8 Tigres UANL 2 Club Leon U21 1 G02:45 | 20/09/25 | R 9 Club Tijuana de Caliente 0 Club Leon U21 1 G18:00 | 23/09/25 | R 10 Club Leon U21 (4) 1 Mazatlan FC U21 (3) 1 G18:00 | 26/09/25 | R 11 FC Juarez U21 1 Club Leon U21 2 M18:00 | 04/10/25 | R 12 Club Leon U21 (3) 2 Deportivo Toluca FC (4) 2 |
| 13 | |  FC Juarez U21 | 12 | 4 | 3 | 5 | 22 | 27 | -5 | 15 | M18:00 | 29/08/25 | R 7 FC Juarez U21 (5) 1 Mazatlan FC U21 (6) 1 M18:00 | 12/09/25 | R 8 Necaxa U21 (5) 0 FC Juarez U21 (4) 0 G18:00 | 19/09/25 | R 9 Cruz Azul 0 FC Juarez U21 1 G18:00 | 23/09/25 | R 10 FC Juarez U21 3 Universidad Nacional U21 0 M18:00 | 26/09/25 | R 11 FC Juarez U21 1 Club Leon U21 2 M18:00 | 03/10/25 | R 12 Atlas FC 4 FC Juarez U21 1 |
| 14 | |  CF Monterrey | 12 | 3 | 4 | 5 | 33 | 40 | -7 | 15 | M18:00 | 23/08/25 | R 6 CF Monterrey (3) 0 Necaxa U21 (4) 0 M18:00 | 29/08/25 | R 7 Puebla U21 (4) 2 CF Monterrey (2) 2 G18:00 | 14/09/25 | R 8 Gallos Blancos de Queretaro 1 CF Monterrey 2 G18:00 | 20/09/25 | R 9 CF Monterrey (7) 2 Club America (6) 2 M18:00 | 27/09/25 | R 11 CF Monterrey 2 Santos Laguna 3 M02:45 | 06/10/25 | R 12 Club Tijuana de Caliente 3 CF Monterrey 1 |
| 15 | |  Atlas FC | 12 | 2 | 5 | 5 | 31 | 34 | -3 | 14 | G18:00 | 24/08/25 | R 6 Atlas FC 1 Club America 0 M18:00 | 31/08/25 | R 7 Universidad Nacional U21 2 Atlas FC 1 G18:00 | 13/09/25 | R 8 Atlas FC (3) 1 Santos Laguna (2) 1 G19:00 | 19/09/25 | R 9 Mazatlan FC U21 (3) 2 Atlas FC (5) 2 M18:00 | 27/09/25 | R 11 Atlas FC 1 Necaxa U21 2 G18:00 | 03/10/25 | R 12 Atlas FC 4 FC Juarez U21 1 |
| 16 | |  Mazatlan FC U21 | 12 | 3 | 3 | 6 | 24 | 32 | -8 | 13 | G18:00 | 29/08/25 | R 7 FC Juarez U21 (5) 1 Mazatlan FC U21 (6) 1 M19:00 | 12/09/25 | R 8 Mazatlan FC U21 0 Universidad Nacional U21 1 M19:00 | 19/09/25 | R 9 Mazatlan FC U21 (3) 2 Atlas FC (5) 2 M18:00 | 23/09/25 | R 10 Club Leon U21 (4) 1 Mazatlan FC U21 (3) 1 M18:00 | 27/09/25 | R 11 Deportivo Toluca FC 4 Mazatlan FC U21 1 G19:00 | 03/10/25 | R 12 Mazatlan FC U21 3 Atletico San Luis 1 |
| 17 | |  Atletico San Luis | 12 | 4 | 1 | 7 | 18 | 27 | -9 | 13 | G18:00 | 22/08/25 | R 6 Gallos Blancos de Queretaro 1 Atletico San Luis 3 M18:00 | 29/08/25 | R 7 Atletico San Luis 0 Deportivo Toluca FC 2 M18:00 | 14/09/25 | R 8 Atletico San Luis 0 Club Tijuana de Caliente 2 M20:00 | 21/09/25 | R 9 Santos Laguna 3 Atletico San Luis 1 G18:15 | 27/09/25 | R 11 Pachuca U21 2 Atletico San Luis 3 M19:00 | 03/10/25 | R 12 Mazatlan FC U21 3 Atletico San Luis 1 |
| 18 | |  Gallos Blancos de Queretaro | 12 | 1 | 4 | 7 | 18 | 31 | -13 | 7 | M18:00 | 22/08/25 | R 6 Gallos Blancos de Queretaro 1 Atletico San Luis 3 M18:00 | 30/08/25 | R 7 Club Leon U21 (5) 2 Gallos Blancos de Queretaro (4) 2 M18:00 | 14/09/25 | R 8 Gallos Blancos de Queretaro 1 CF Monterrey 2 M18:15 | 20/09/25 | R 9 Pachuca U21 (4) 1 Gallos Blancos de Queretaro (3) 1 M18:00 | 28/09/25 | R 11 Gallos Blancos de Queretaro 0 Tigres UANL 1 G18:00 | 04/10/25 | R 12 Gallos Blancos de Queretaro 2 Puebla U21 0 |
